Can users change Shopify region settings?

Yes, but Shopify region settings depend on what the user wants to change.

• Store country/region: The store’s country or region can be changed in Shopify admin, although changing it may affect currency, taxes, payments, and other settings.
• Shopify Markets: Merchants can add or configure countries and regions they sell to through Markets.
• Account region: Some account-related regional information may be determined by Shopify and may have specific requirements for changing it.

Because regional changes can affect important store settings, merchants should review payment, tax, currency, and market configurations after making changes.